C M L (Chronic myelogenous (or myeloid) leukemia)
Chronic myelogenous (or myeloid) leukemia (CML) is a cancer of the white blood cells. It is a form of leukemia characterized by the increased and unregulated growth of predominantly myeloid cells in the bone marrow and the accumulation of these cells in the blood.
CML is an acquired leukemia, resulting from a change in a person's DNA. This change results in an uncontrolled growth of white cells. This uncontrolled growth can bring about abdominal discomfort due to an enlarged spleen. Other symptoms may include excessive sweating (night sweats), weight loss, and an increased sensitivity to warm temperatures. CML has three phases: 1) chronic phase; 2) accelerated phase: and 3) blastic or blast crisis.
(CML does NOT have "stages" like other cancers.)
Chronic phase, the beginning phase in which most patients (approximately 80%) are diagnosed, presents with symptoms being less severe due to the cell's ability to continue to develop into functioning white cells and platelets.
Accelerated phase marks a point in which the "disease load" has increased. Generally, at this phase, blast cells (immature white blood cells) make up 10% to 15% of peripheral blood or bone marrow. More symptoms may begin to appear and platelet levels may begin to fluctuate erratically.
Blastic (or Blast Crisis) is the most advanced phase of the disease and is indicated by a blast percentage greater than 30%. Symptoms include those mentioned above, as well as bone pain, infection, acute bruising and bleeding. Bruising and seepage of blood into the skin is a primary feature of this phase. Some patients may also experience extreme fatigue, shortness of breath, and abdominal pain. Blast crisis closely resembles acute leukemia and has a survival range of three to six months.
CML is an acquired leukemia, resulting from a change in a person's DNA. This change results in an uncontrolled growth of white cells. This uncontrolled growth can bring about abdominal discomfort due to an enlarged spleen. Other symptoms may include excessive sweating (night sweats), weight loss, and an increased sensitivity to warm temperatures. CML has three phases: 1) chronic phase; 2) accelerated phase: and 3) blastic or blast crisis.
(CML does NOT have "stages" like other cancers.)
Chronic phase, the beginning phase in which most patients (approximately 80%) are diagnosed, presents with symptoms being less severe due to the cell's ability to continue to develop into functioning white cells and platelets.
Accelerated phase marks a point in which the "disease load" has increased. Generally, at this phase, blast cells (immature white blood cells) make up 10% to 15% of peripheral blood or bone marrow. More symptoms may begin to appear and platelet levels may begin to fluctuate erratically.
Blastic (or Blast Crisis) is the most advanced phase of the disease and is indicated by a blast percentage greater than 30%. Symptoms include those mentioned above, as well as bone pain, infection, acute bruising and bleeding. Bruising and seepage of blood into the skin is a primary feature of this phase. Some patients may also experience extreme fatigue, shortness of breath, and abdominal pain. Blast crisis closely resembles acute leukemia and has a survival range of three to six months.
Now i am in Accelerated Phase
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